生物製劑特性鑑別(M) - 艾默生物醫學股份有限公司

生物製劑特性鑑別
(Biological Characterization for Biopharmaceutics)

● 抗體依賴型之細胞介導的細胞毒殺作用(Antibody-Dependent Cell-mediated Cytotoxicity, ADCC)

● Effector cells的來源為PBMC或純化的NK細胞，依您需求使用冷凍細胞或新鮮自全血分離的細胞

● Target cells依您的需求使用癌細胞株或primary cell

● 補體介導的細胞毒殺作用 (Complement-Dependent Cytotoxicity Assay, CDC)

● 中和試驗 (Neutralization Assay)

● Neutralizing target: Cytokines

● Cell-Based Assay

● 配體結合分析 (Ligand-Binding Assay)

● ELISA

● Flow-cytometry

● 細胞凋亡檢測 (Apoptosis Assay)

● 細胞增生檢測 (Cell Proliferation Assay)

● MTT Assay

● LDH Assay

● Flow-cytometry